First human experiments with a novel non-invasive, non-optical continuous glucose monitoring system

Hdl Handle:
http://hdl.handle.net/10149/58359
Title:
First human experiments with a novel non-invasive, non-optical continuous glucose monitoring system
Authors:
Caduff, A. (Andreas); Hirt, E. (Etienne); Feldman, Y. D. (Yu); Ali, Z. (Zulfiqur); Heinemann, L. (Lutz)
Affiliation:
Pendragon Medical. Zurich. Switzerland; Profil Institute for Metabolic Research. Neuss. Germany; University of Teesside.
Citation:
Caduff, A. et al. (2003) 'First human experiments with a novel non-invasive, non-optical continuous glucose monitoring system', Biosensors and Bioelectronics, 19 (3), pp.209-217.
Publisher:
Elsevier
Journal:
Biosensors and Bioelectronics
Issue Date:
Nov-2003
URI:
http://hdl.handle.net/10149/58359
DOI:
10.1016/S0956-5663(03)00196-9
Abstract:
This paper describes a non-invasive continuous glucose monitoring system based on impedance spectroscopy. Changes in the glucose concentrations can be monitored by varying the frequency in the radio band over a range, optimised to measure the impact of glucose on the impedance pattern. A number of clinical-experimental studies (hyperglycaemic excursions) were performed with healthy subjects in order to prove the applicability of this approach. The sensor used in these experiments is the size of a wristwatch and holds an open resonant circuit coupled to the skin and a circuit, performing an impedance measurement. In most cases, the experiments showed a good correlation between changes in blood glucose and the sensor recordings. A detailed description of the trials is presented. The results of this first series of experiments can be considered as a proof of concept for this novel non-invasive monitoring approach. Nevertheless, partly due to the indirect measurement, a considerable number of questions remain to be clarified.
Type:
Article
Keywords:
non-invasive blood glucose monitoring; non-invasive; glucose monitoring; impedance spectroscopy; non-optical blood glucose monitoring; non-optical; hyperglycaemic excursions
ISSN:
0956-5663
Rights:
Author can archive post-print (ie final draft post-refereeing). For full details see http://www.sherpa.ac.uk/romeo/ [Accessed 18/12/09]
Citation Count:
48 [Scopus, 18/12/09]

Full metadata record

DC FieldValue Language
dc.contributor.authorCaduff, A. (Andreas)-
dc.contributor.authorHirt, E. (Etienne)-
dc.contributor.authorFeldman, Y. D. (Yu)-
dc.contributor.authorAli, Z. (Zulfiqur)-
dc.contributor.authorHeinemann, L. (Lutz)-
dc.date.accessioned2009-04-01T10:50:00Z-
dc.date.available2009-04-01T10:50:00Z-
dc.date.issued2003-11-
dc.identifier.citationBiosensors and Bioelectronics; 19 (3): 209-217-
dc.identifier.issn0956-5663-
dc.identifier.doi10.1016/S0956-5663(03)00196-9-
dc.identifier.urihttp://hdl.handle.net/10149/58359-
dc.description.abstractThis paper describes a non-invasive continuous glucose monitoring system based on impedance spectroscopy. Changes in the glucose concentrations can be monitored by varying the frequency in the radio band over a range, optimised to measure the impact of glucose on the impedance pattern. A number of clinical-experimental studies (hyperglycaemic excursions) were performed with healthy subjects in order to prove the applicability of this approach. The sensor used in these experiments is the size of a wristwatch and holds an open resonant circuit coupled to the skin and a circuit, performing an impedance measurement. In most cases, the experiments showed a good correlation between changes in blood glucose and the sensor recordings. A detailed description of the trials is presented. The results of this first series of experiments can be considered as a proof of concept for this novel non-invasive monitoring approach. Nevertheless, partly due to the indirect measurement, a considerable number of questions remain to be clarified.-
dc.publisherElsevier-
dc.rightsAuthor can archive post-print (ie final draft post-refereeing). For full details see http://www.sherpa.ac.uk/romeo/ [Accessed 18/12/09]-
dc.subjectnon-invasive blood glucose monitoring-
dc.subjectnon-invasive-
dc.subjectglucose monitoring-
dc.subjectimpedance spectroscopy-
dc.subjectnon-optical blood glucose monitoring-
dc.subjectnon-optical-
dc.subjecthyperglycaemic excursions-
dc.titleFirst human experiments with a novel non-invasive, non-optical continuous glucose monitoring system-
dc.typeArticle-
dc.contributor.departmentPendragon Medical. Zurich. Switzerland; Profil Institute for Metabolic Research. Neuss. Germany; University of Teesside.-
dc.identifier.journalBiosensors and Bioelectronics-
ref.assessmentRAE 2008-
ref.citationcount48 [Scopus, 18/12/09]-
or.citation.harvardCaduff, A. et al. (2003) 'First human experiments with a novel non-invasive, non-optical continuous glucose monitoring system', Biosensors and Bioelectronics, 19 (3), pp.209-217.-
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