Interpretation of two-dimensional and tissue Doppler-derived strain (epsilon) and strain rate data: is there a need to normalize for individual variability in left ventricular morphology?

Hdl Handle:
http://hdl.handle.net/10149/91868
Title:
Interpretation of two-dimensional and tissue Doppler-derived strain (epsilon) and strain rate data: is there a need to normalize for individual variability in left ventricular morphology?
Authors:
Oxborough, D. (David); Batterham, A. M. (Alan); Shave, R. (Rob); Artis, N. (Nigel); Birch, K. M. (Karen); Whyte, G. (Greg); Ainslie, P. N. (Philip); George, K. P. (Keith)
Affiliation:
University of Teesside. Health and Social Care Institute.
Citation:
Oxborough, D. et al. (2009) 'Interpretation of two-dimensional and tissue Doppler-derived strain (epsilon) and strain rate data: is there a need to normalize for individual variability in left ventricular morphology?', European Journal of Echocardiography, 10 (5), pp.677-682.
Publisher:
Elsevier
Journal:
European Journal of Echocardiography
Issue Date:
Jul-2009
URI:
http://hdl.handle.net/10149/91868
DOI:
10.1093/ejechocard/jep037
Abstract:
Aims: This study examined the relationships between myocardial strain () and strain rate (SR) data, derived from both two-dimensional (2D) speckle tracking and tissue Doppler imaging (TDI), and indices of left ventricular (LV) morphology to assess size-(in)dependence of these functional parameters. Methods and results: 2D speckle tracking and TDI echocardiograms were performed in 79 healthy adult male volunteers (age range: 22–76 years). 2D speckle tracking allowed the determination of myocardial and peak systolic and early diastolic SR in radial, circumferential, and longitudinal planes, whereas TDI provided longitudinal only. Mean circumferential and radial and SR were calculated from data collected at six basal myocardial regions, whereas mean longitudinal and SR derived from both 2D speckle tracking and TDI were calculated from the basal septum and basal lateral walls. Standard 2D echocardiography allowed the assessment of LV morphology including LV length, LV end-diastolic volume, LV end-diastolic diameter, mean wall thickness, and LV mass. The association of myocardial and SR data with relevant LV morphology indices was determined by adoption of the general, non-linear allometric model (y= axb). The b exponent ± 95% confidence intervals were reported. The relationships between the measures of LV morphology and myocardial and SR were highly variable and generally weak. Only two relationships displayed at least a moderate effect size (r 0.30): (i) 2D circumferential peak systolic SR and LV end-diastolic dimension (b = –0.92; –1.35 to 0.5, r = 0.44) and (ii) TDI longitudinal peak systolic SR and LV length (b = –1.39; –2.11 to –0.66, r = 0.41). Conclusion: The empirical relationships derived in this cohort do not support the need to scale myocardial and SR derived from 2D speckle or TDI for any index of LV morphology.
Type:
Article
Language:
en
Keywords:
speckle tracking; tissue doppler; left ventricle; scaling; allometry
ISSN:
1525-2167; 1532-2114
Rights:
Author can archive post-print (ie final draft post-refereeing). For full details see http://www.sherpa.ac.uk/romeo/ [Accessed 11/02/2010]
Citation Count:
1 [Scopus, 11/02/2010]

Full metadata record

DC FieldValue Language
dc.contributor.authorOxborough, D. (David)en
dc.contributor.authorBatterham, A. M. (Alan)en
dc.contributor.authorShave, R. (Rob)en
dc.contributor.authorArtis, N. (Nigel)en
dc.contributor.authorBirch, K. M. (Karen)en
dc.contributor.authorWhyte, G. (Greg)en
dc.contributor.authorAinslie, P. N. (Philip)en
dc.contributor.authorGeorge, K. P. (Keith)en
dc.date.accessioned2010-02-11T15:32:39Z-
dc.date.available2010-02-11T15:32:39Z-
dc.date.issued2009-07-
dc.identifier.citationEuropean Journal of Echocardiography; 10 (5): 677-682en
dc.identifier.issn1525-2167-
dc.identifier.issn1532-2114-
dc.identifier.doi10.1093/ejechocard/jep037-
dc.identifier.urihttp://hdl.handle.net/10149/91868-
dc.description.abstractAims: This study examined the relationships between myocardial strain () and strain rate (SR) data, derived from both two-dimensional (2D) speckle tracking and tissue Doppler imaging (TDI), and indices of left ventricular (LV) morphology to assess size-(in)dependence of these functional parameters. Methods and results: 2D speckle tracking and TDI echocardiograms were performed in 79 healthy adult male volunteers (age range: 22–76 years). 2D speckle tracking allowed the determination of myocardial and peak systolic and early diastolic SR in radial, circumferential, and longitudinal planes, whereas TDI provided longitudinal only. Mean circumferential and radial and SR were calculated from data collected at six basal myocardial regions, whereas mean longitudinal and SR derived from both 2D speckle tracking and TDI were calculated from the basal septum and basal lateral walls. Standard 2D echocardiography allowed the assessment of LV morphology including LV length, LV end-diastolic volume, LV end-diastolic diameter, mean wall thickness, and LV mass. The association of myocardial and SR data with relevant LV morphology indices was determined by adoption of the general, non-linear allometric model (y= axb). The b exponent ± 95% confidence intervals were reported. The relationships between the measures of LV morphology and myocardial and SR were highly variable and generally weak. Only two relationships displayed at least a moderate effect size (r 0.30): (i) 2D circumferential peak systolic SR and LV end-diastolic dimension (b = –0.92; –1.35 to 0.5, r = 0.44) and (ii) TDI longitudinal peak systolic SR and LV length (b = –1.39; –2.11 to –0.66, r = 0.41). Conclusion: The empirical relationships derived in this cohort do not support the need to scale myocardial and SR derived from 2D speckle or TDI for any index of LV morphology.en
dc.language.isoenen
dc.publisherElsevieren
dc.rightsAuthor can archive post-print (ie final draft post-refereeing). For full details see http://www.sherpa.ac.uk/romeo/ [Accessed 11/02/2010]en
dc.subjectspeckle trackingen
dc.subjecttissue doppleren
dc.subjectleft ventricleen
dc.subjectscalingen
dc.subjectallometryen
dc.titleInterpretation of two-dimensional and tissue Doppler-derived strain (epsilon) and strain rate data: is there a need to normalize for individual variability in left ventricular morphology?en
dc.typeArticleen
dc.contributor.departmentUniversity of Teesside. Health and Social Care Institute.en
dc.identifier.journalEuropean Journal of Echocardiographyen
ref.citationcount1 [Scopus, 11/02/2010]en
or.citation.harvardOxborough, D. et al. (2009) 'Interpretation of two-dimensional and tissue Doppler-derived strain (epsilon) and strain rate data: is there a need to normalize for individual variability in left ventricular morphology?', European Journal of Echocardiography, 10 (5), pp.677-682.-
All Items in TeesRep are protected by copyright, with all rights reserved, unless otherwise indicated.