Displacing sedentary time: Association with cardiovascular disease prevalence

Hdl Handle:
http://hdl.handle.net/10149/582104
Title:
Displacing sedentary time: Association with cardiovascular disease prevalence
Authors:
Wellburn, S. (Shaun); Ryan, C. G. (Cormac); Azevedo, L. B. (Liane); Ells, L. J. (Louisa); Martin, D. J. (Denis); Atkinson, G. (Greg); Batterham, A. M. (Alan)
Affiliation:
Teesside University. Health and Social Care Institute.
Citation:
Wellburn, S., Ryan, C. G., Azevedo, L. B., Ells, L. J., Martin, D. J., Atkinson, G., Batterham, A. M. (2015) 'Displacing sedentary time: Association with cardiovascular disease prevalence' Medicine & Science in Sports & Exercise; Published ahead of print 19 Nov 2015
Publisher:
Lippincott, Williams & Wilkins
Journal:
Medicine & Science in Sports & Exercise
Issue Date:
12-Nov-2015
URI:
http://hdl.handle.net/10149/582104
DOI:
10.1249/MSS.0000000000000816
Additional Links:
http://journals.lww.com/acsm-msse/Abstract/publishahead/Displacing_Sedentary_Time___Association_with.97660.aspx
Abstract:
Purpose: Isotemporal substitution analysis offers new insights for public health, but has only recently been applied to sedentary behavior research. We aimed to quantify associations between the substitution of 10 minutes of sedentary behavior with 10 minutes of light physical activity (LPA) or moderate-to-vigorous physical activity (MVPA) and the prevalence of cardiovascular disease (CVD). Age was also explored as a potential effect modifier. Methods: We completed a secondary analysis of data from 1477 adults from the Health Survey for England (2008). Sedentary time, LPA and MVPA were measured using accelerometry. We applied isotemporal models to quantify the relationship with CVD prevalence of replacing 10 minutes of sedentary time with equivalent amounts of LPA or MVPA. Prevalence risk ratios (RR) with 95% confidence intervals (CI) are presented, adjusted for covariates. The role of age as an effect modifier was explored via age × MVPA and age × LPA interactions. CVD was defined as per the International Classification of Diseases. Results: The prevalence of CVD was 24%. The RR was 0.97 (95% CI: 0.96 to 0.99) for LPA and 0.88 (0.81 to 0.96) for MVPA. Substitution of approximately 50 minutes of LPA would be required for an association equivalent to 10 minutes of MVPA. The beneficial association of MVPA was attenuated with age, with a decrease in the relative risk reduction of ~7% per decade. Conclusions: Isotemporal substitution of sedentary time with LPA was associated with a trivial relative risk reduction for CVD, whereas the equivalent replacement with MVPA had a small beneficial relationship. With respect to CVD prevalence, MVPA might become decreasingly important in older individuals. Prospective studies are needed to investigate causality.
Type:
Article
Language:
en
Keywords:
Isotemporal substitution; public health; prevalence risk ratio; physical activity
ISSN:
0195-9131
Rights:
Following 12 month embargo author can archive post-print (ie final draft post-refereeing). For full details see http://www.sherpa.ac.uk/romeo [Accessed: 12/11/2015]

Full metadata record

DC FieldValue Language
dc.contributor.authorWellburn, S. (Shaun)en
dc.contributor.authorRyan, C. G. (Cormac)en
dc.contributor.authorAzevedo, L. B. (Liane)en
dc.contributor.authorElls, L. J. (Louisa)en
dc.contributor.authorMartin, D. J. (Denis)en
dc.contributor.authorAtkinson, G. (Greg)en
dc.contributor.authorBatterham, A. M. (Alan)en
dc.date.accessioned2015-11-12T14:19:23Zen
dc.date.available2015-11-12T14:19:23Zen
dc.date.issued2015-11-12en
dc.identifier.citationMedicine & Science in Sports & Exercise; Published ahead of print 19 Nov 2015en
dc.identifier.issn0195-9131en
dc.identifier.doi10.1249/MSS.0000000000000816en
dc.identifier.urihttp://hdl.handle.net/10149/582104en
dc.description.abstractPurpose: Isotemporal substitution analysis offers new insights for public health, but has only recently been applied to sedentary behavior research. We aimed to quantify associations between the substitution of 10 minutes of sedentary behavior with 10 minutes of light physical activity (LPA) or moderate-to-vigorous physical activity (MVPA) and the prevalence of cardiovascular disease (CVD). Age was also explored as a potential effect modifier. Methods: We completed a secondary analysis of data from 1477 adults from the Health Survey for England (2008). Sedentary time, LPA and MVPA were measured using accelerometry. We applied isotemporal models to quantify the relationship with CVD prevalence of replacing 10 minutes of sedentary time with equivalent amounts of LPA or MVPA. Prevalence risk ratios (RR) with 95% confidence intervals (CI) are presented, adjusted for covariates. The role of age as an effect modifier was explored via age × MVPA and age × LPA interactions. CVD was defined as per the International Classification of Diseases. Results: The prevalence of CVD was 24%. The RR was 0.97 (95% CI: 0.96 to 0.99) for LPA and 0.88 (0.81 to 0.96) for MVPA. Substitution of approximately 50 minutes of LPA would be required for an association equivalent to 10 minutes of MVPA. The beneficial association of MVPA was attenuated with age, with a decrease in the relative risk reduction of ~7% per decade. Conclusions: Isotemporal substitution of sedentary time with LPA was associated with a trivial relative risk reduction for CVD, whereas the equivalent replacement with MVPA had a small beneficial relationship. With respect to CVD prevalence, MVPA might become decreasingly important in older individuals. Prospective studies are needed to investigate causality.en
dc.language.isoenen
dc.publisherLippincott, Williams & Wilkinsen
dc.relation.urlhttp://journals.lww.com/acsm-msse/Abstract/publishahead/Displacing_Sedentary_Time___Association_with.97660.aspxen
dc.rightsFollowing 12 month embargo author can archive post-print (ie final draft post-refereeing). For full details see http://www.sherpa.ac.uk/romeo [Accessed: 12/11/2015]en
dc.subjectIsotemporal substitutionen
dc.subjectpublic healthen
dc.subjectprevalence risk ratioen
dc.subjectphysical activityen
dc.titleDisplacing sedentary time: Association with cardiovascular disease prevalenceen
dc.typeArticleen
dc.contributor.departmentTeesside University. Health and Social Care Institute.en
dc.identifier.journalMedicine & Science in Sports & Exerciseen
or.citation.harvardWellburn, S., Ryan, C. G., Azevedo, L. B., Ells, L. J., Martin, D. J., Atkinson, G., Batterham, A. M. (2015) 'Displacing sedentary time: Association with cardiovascular disease prevalence' Medicine & Science in Sports & Exercise; Published ahead of print 19 Nov 2015en
dc.date.accepted2015-11-03en
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