Influence of hyperoxia on pulmonary O2 uptake kinetics following the onset of exercise in humans

Hdl Handle:
http://hdl.handle.net/10149/96906
Title:
Influence of hyperoxia on pulmonary O2 uptake kinetics following the onset of exercise in humans
Authors:
Wilkerson, D. P. (Daryl); Berger, N. J. A. (Nicolas); Jones, A. M. (Andrew)
Affiliation:
Manchester Metropolitan University. Department of Exercise and Sport Science.
Citation:
Wilkerson, D. P., Berger, N. J. A. and Jones, A. M. (2006) 'Influence of hyperoxia on pulmonary O2 uptake kinetics following the onset of exercise in humans', Respiratory Physiology & Neurobiology, 153 (1), pp.92-106.
Publisher:
Elsevier
Journal:
Respiratory Physiology & Neurobiology
Issue Date:
Aug-2006
URI:
http://hdl.handle.net/10149/96906
DOI:
10.1016/j.resp.2005.09.006
Abstract:
The purpose of this study was to examine the influence of hyperoxic gas (50% O2 in N2) inspiration on pulmonary oxygen uptake (over(V, ̇)O2) kinetics during step transitions to moderate, severe and supra-maximal intensity cycle exercise. Seven healthy male subjects completed repeat transitions to moderate (90% of the gas exchange threshold, GET), severe (70% of the difference between the GET and over(V, ̇)O2 peak) and supra-maximal (105% over(V, ̇)O2 peak) intensity work rates while breathing either normoxic (N) or hyperoxic (H) gas before and during exercise. Hyperoxia had no significant effect on the Phase II over(V, ̇)O2 time constant during moderate (N: 28 ± 3 s versus H: 31 ± 7 s), severe (N: 32 ± 9 s versus H: 33 ± 6 s) or supra-maximal (N: 37 ± 9 s versus H: 37 ± 9 s) exercise. Hyperoxia resulted in a 45% reduction in the amplitude of the over(V, ̇)O2 slow component during severe exercise (N: 0.60 ± 0.21 L min-1 versus H: 0.33 ± 0.17 L min-1; P < 0.05) and a 15% extension of time to exhaustion during supra-maximal exercise (N: 173 ± 28 s versus H: 198 ± 41 s; P < 0.05). These results indicate that the Phase II over(V, ̇)O2 kinetics are not normally constrained by (diffusional) O2 transport limitations during moderate, severe or supra-maximal intensity exercise in young healthy subjects performing upright cycle exercise.
Type:
Article
Language:
en
Keywords:
exercise; O2 consumption; O2 dynamics; O2 transport; slow component; oxygen uptake; respiratory gas exchange
ISSN:
1569-9048
Rights:
Author can archive post-print (ie final draft post-refereeing). For full details see http://www.sherpa.ac.uk/romeo/ [Accessed 20/04/2010]
Citation Count:
21 [Scopus, 20/04/2010]

Full metadata record

DC FieldValue Language
dc.contributor.authorWilkerson, D. P. (Daryl)en
dc.contributor.authorBerger, N. J. A. (Nicolas)en
dc.contributor.authorJones, A. M. (Andrew)en
dc.date.accessioned2010-04-20T12:50:56Z-
dc.date.available2010-04-20T12:50:56Z-
dc.date.issued2006-08-
dc.identifier.citationRespiratory Physiology & Neurobiology; 153 (1): 92-106en
dc.identifier.issn1569-9048-
dc.identifier.doi10.1016/j.resp.2005.09.006-
dc.identifier.urihttp://hdl.handle.net/10149/96906-
dc.description.abstractThe purpose of this study was to examine the influence of hyperoxic gas (50% O2 in N2) inspiration on pulmonary oxygen uptake (over(V, ̇)O2) kinetics during step transitions to moderate, severe and supra-maximal intensity cycle exercise. Seven healthy male subjects completed repeat transitions to moderate (90% of the gas exchange threshold, GET), severe (70% of the difference between the GET and over(V, ̇)O2 peak) and supra-maximal (105% over(V, ̇)O2 peak) intensity work rates while breathing either normoxic (N) or hyperoxic (H) gas before and during exercise. Hyperoxia had no significant effect on the Phase II over(V, ̇)O2 time constant during moderate (N: 28 ± 3 s versus H: 31 ± 7 s), severe (N: 32 ± 9 s versus H: 33 ± 6 s) or supra-maximal (N: 37 ± 9 s versus H: 37 ± 9 s) exercise. Hyperoxia resulted in a 45% reduction in the amplitude of the over(V, ̇)O2 slow component during severe exercise (N: 0.60 ± 0.21 L min-1 versus H: 0.33 ± 0.17 L min-1; P < 0.05) and a 15% extension of time to exhaustion during supra-maximal exercise (N: 173 ± 28 s versus H: 198 ± 41 s; P < 0.05). These results indicate that the Phase II over(V, ̇)O2 kinetics are not normally constrained by (diffusional) O2 transport limitations during moderate, severe or supra-maximal intensity exercise in young healthy subjects performing upright cycle exercise.en
dc.language.isoenen
dc.publisherElsevieren
dc.rightsAuthor can archive post-print (ie final draft post-refereeing). For full details see http://www.sherpa.ac.uk/romeo/ [Accessed 20/04/2010]en
dc.subjectexerciseen
dc.subjectO2 consumptionen
dc.subjectO2 dynamicsen
dc.subjectO2 transporten
dc.subjectslow componenten
dc.subjectoxygen uptakeen
dc.subjectrespiratory gas exchangeen
dc.titleInfluence of hyperoxia on pulmonary O2 uptake kinetics following the onset of exercise in humansen
dc.typeArticleen
dc.contributor.departmentManchester Metropolitan University. Department of Exercise and Sport Science.en
dc.identifier.journalRespiratory Physiology & Neurobiologyen
ref.citationcount21 [Scopus, 20/04/2010]en
or.citation.harvardWilkerson, D. P., Berger, N. J. A. and Jones, A. M. (2006) 'Influence of hyperoxia on pulmonary O2 uptake kinetics following the onset of exercise in humans', Respiratory Physiology & Neurobiology, 153 (1), pp.92-106.-
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