A novel point of care diagnostic device: Impedimetric detection of a biomarker in whole blood

Hdl Handle:
http://hdl.handle.net/10149/98057
Title:
A novel point of care diagnostic device: Impedimetric detection of a biomarker in whole blood
Book Title:
Proceedings of the 29th annual international conference of the IEEE EMBS
Authors:
McMurray, A. A. (Amanda); Ali, Z. (Zulfiqur); Kyselovik, J. (Jan); Mills, C. A. (Christopher); Jaffrezic-Renault, N. (Nicole); Santha, H. (Hunor); Strohhöfer, C. (Christof)
Affiliation:
The Centre of Excellence in Nano and Micro Photonic Systems
Citation:
McMurray, A. A. et. al. (2007) 'A novel point of care diagnostic device: Impedimetric detection of a biomarker in whole blood', Annual international conference of the IEEE engineering in medicine and biology society, Cité Internationale, Lyon, France, August 23-26, in Proceedings of the 29th annual international conference of the IEEE EMBS. IEEE, pp.115-118.
Publisher:
IEEE
Conference:
Annual international conference of the IEEE engineering in medicine and biology society, Cité Internationale, Lyon, France, August 23-26, 2007.
Issue Date:
2007
URI:
http://hdl.handle.net/10149/98057
Additional Links:
http://ieeexplore.ieee.org/stamp/stamp.jsp?arnumber=04352236
Abstract:
There is an unmet medical need for a more reliable and earlier assessment of patients suspected of having a deep vein thrombosis. We describe a novel approach which is developing a highly reliable, accurate, portable and handheld prototype medical diagnostic device to improve radically the speed, accuracy and reliability with which DVT and related blood clotting conditions can be assessed. The device will measure whole blood concentration of D-dimer, a recognized biomarker of increased blood clotting activity, and through innovation in the development of a novel detection, measurement and reporting system, will offer the opportunity to use the test in the point of care setting. The device combines innovation in antibody bio-engineering for high specificity immunoassay-based diagnostics and nano/micro engineered impedimetric analysis electrodes incorporating a biocompatible polymer substrate with development of a disposable microfluidic manifold specifically enabling diagnostics at the point-of-first-contact.
Type:
Meetings and Proceedings; Book Chapter
Language:
en
Keywords:
deep vein thrombosis; diagnosis; reliable; accurate; device
ISSN:
1557170X
Rights:
Author can archive publisher's version/PDF. For full details see http://www.sherpa.ac.uk/romeo/ [Accessed 06/05/2010]
Citation Count:
0 [Scopus, 06/05/2010]

Full metadata record

DC FieldValue Language
dc.contributor.authorMcMurray, A. A. (Amanda)en
dc.contributor.authorAli, Z. (Zulfiqur)en
dc.contributor.authorKyselovik, J. (Jan)en
dc.contributor.authorMills, C. A. (Christopher)en
dc.contributor.authorJaffrezic-Renault, N. (Nicole)en
dc.contributor.authorSantha, H. (Hunor)en
dc.contributor.authorStrohhöfer, C. (Christof)en
dc.date.accessioned2010-05-06T14:00:34Z-
dc.date.available2010-05-06T14:00:34Z-
dc.date.issued2007-
dc.identifier.issn1557170X-
dc.identifier.urihttp://hdl.handle.net/10149/98057-
dc.description.abstractThere is an unmet medical need for a more reliable and earlier assessment of patients suspected of having a deep vein thrombosis. We describe a novel approach which is developing a highly reliable, accurate, portable and handheld prototype medical diagnostic device to improve radically the speed, accuracy and reliability with which DVT and related blood clotting conditions can be assessed. The device will measure whole blood concentration of D-dimer, a recognized biomarker of increased blood clotting activity, and through innovation in the development of a novel detection, measurement and reporting system, will offer the opportunity to use the test in the point of care setting. The device combines innovation in antibody bio-engineering for high specificity immunoassay-based diagnostics and nano/micro engineered impedimetric analysis electrodes incorporating a biocompatible polymer substrate with development of a disposable microfluidic manifold specifically enabling diagnostics at the point-of-first-contact.en
dc.language.isoenen
dc.publisherIEEEen
dc.relation.urlhttp://ieeexplore.ieee.org/stamp/stamp.jsp?arnumber=04352236en
dc.rightsAuthor can archive publisher's version/PDF. For full details see http://www.sherpa.ac.uk/romeo/ [Accessed 06/05/2010]en
dc.subjectdeep vein thrombosisen
dc.subjectdiagnosisen
dc.subjectreliableen
dc.subjectaccurateen
dc.subjectdeviceen
dc.titleA novel point of care diagnostic device: Impedimetric detection of a biomarker in whole blooden
dc.typeMeetings and Proceedingsen
dc.typeBook Chapteren
dc.contributor.departmentThe Centre of Excellence in Nano and Micro Photonic Systemsen
dc.title.bookProceedings of the 29th annual international conference of the IEEE EMBSen
dc.identifier.conferenceAnnual international conference of the IEEE engineering in medicine and biology society, Cité Internationale, Lyon, France, August 23-26, 2007.en
ref.citationcount0 [Scopus, 06/05/2010]en
or.citation.harvardMcMurray, A. A. et. al. (2007) 'A novel point of care diagnostic device: Impedimetric detection of a biomarker in whole blood', Annual international conference of the IEEE engineering in medicine and biology society, Cité Internationale, Lyon, France, August 23-26, in Proceedings of the 29th annual international conference of the IEEE EMBS. IEEE, pp.115-118.-
prism.startingPage115-
prism.endingPage118-
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