Bone mineral change during experimental heating: an X-ray scattering investigation

Hdl Handle:
http://hdl.handle.net/10149/99313
Title:
Bone mineral change during experimental heating: an X-ray scattering investigation
Authors:
Hiller, J. (Jennifer); Thompson, T. J. U. (Tim); Evison, M. P. (Martin); Chamberlain, A. T. (Andrew); Wess, T. J. (Timothy)
Affiliation:
University of Sheffield. Medico-Legal Centre. Department of Forensic Pathology.
Citation:
Hiller, J. et. al. (2003) 'Bone mineral change during experimental heating: an X-ray scattering investigation', Biomaterials, 24 (28), pp.5091-5097.
Publisher:
Elsevier
Journal:
Biomaterials
Issue Date:
Dec-2003
URI:
http://hdl.handle.net/10149/99313
DOI:
10.1016/S0142-9612(03)00427-7
Abstract:
The effects of heating and burning on bone mineral have previously been studied using techniques such as X-ray diffraction (XRD) with the aim of discerning a characteristic signature of crystal change. This would enable a better understanding of alteration to bone mineral during heating, which would in turn impact on the preparation and use of natural bone hydroxyapatite as a biomaterial resource. In addition, this knowledge could prove invaluable in the investigation of burned human remains from forensic and archaeological contexts in cremation and funerary practice. Here we describe a complementary method, small-angle X-ray scattering (SAXS), to determine more accurately the changes to bone crystallite size and shape during an experimental heating regimen. Samples were subjected to controlled heating at 500°C, 700°C, or 900°C for 15 or 45min. Our results show bone crystallites begin to alter in the first 15min of heating to 500°C or above. They then appear to stabilise to a temperature-specific thickness and shape with prolonged heating. While the samples heated to lower temperatures or for shorter periods produce XRD traces showing little alteration to the apatite, corresponding information obtained from SAXS shows an early, subtle change in crystal parameters.
Type:
Article
Language:
en
Keywords:
bone; crystal growth; hydroxyapatite; microstructure; XRD
ISSN:
0142-9612
Rights:
Author can archive post-print (ie final draft post-refereeing). For full details see http://www.sherpa.ac.uk/romeo/ [Accessed 19/05/2010]
Citation Count:
42 [Scopus, 19/05/2010]

Full metadata record

DC FieldValue Language
dc.contributor.authorHiller, J. (Jennifer)en
dc.contributor.authorThompson, T. J. U. (Tim)en
dc.contributor.authorEvison, M. P. (Martin)en
dc.contributor.authorChamberlain, A. T. (Andrew)en
dc.contributor.authorWess, T. J. (Timothy)en
dc.date.accessioned2010-05-19T12:30:08Z-
dc.date.available2010-05-19T12:30:08Z-
dc.date.issued2003-12-
dc.identifier.citationBiomaterials; 24(28):5091-5097en
dc.identifier.issn0142-9612-
dc.identifier.doi10.1016/S0142-9612(03)00427-7-
dc.identifier.urihttp://hdl.handle.net/10149/99313-
dc.description.abstractThe effects of heating and burning on bone mineral have previously been studied using techniques such as X-ray diffraction (XRD) with the aim of discerning a characteristic signature of crystal change. This would enable a better understanding of alteration to bone mineral during heating, which would in turn impact on the preparation and use of natural bone hydroxyapatite as a biomaterial resource. In addition, this knowledge could prove invaluable in the investigation of burned human remains from forensic and archaeological contexts in cremation and funerary practice. Here we describe a complementary method, small-angle X-ray scattering (SAXS), to determine more accurately the changes to bone crystallite size and shape during an experimental heating regimen. Samples were subjected to controlled heating at 500°C, 700°C, or 900°C for 15 or 45min. Our results show bone crystallites begin to alter in the first 15min of heating to 500°C or above. They then appear to stabilise to a temperature-specific thickness and shape with prolonged heating. While the samples heated to lower temperatures or for shorter periods produce XRD traces showing little alteration to the apatite, corresponding information obtained from SAXS shows an early, subtle change in crystal parameters.en
dc.language.isoenen
dc.publisherElsevieren
dc.rightsAuthor can archive post-print (ie final draft post-refereeing). For full details see http://www.sherpa.ac.uk/romeo/ [Accessed 19/05/2010]en
dc.subjectboneen
dc.subjectcrystal growthen
dc.subjecthydroxyapatiteen
dc.subjectmicrostructureen
dc.subjectXRDen
dc.titleBone mineral change during experimental heating: an X-ray scattering investigationen
dc.typeArticleen
dc.contributor.departmentUniversity of Sheffield. Medico-Legal Centre. Department of Forensic Pathology.en
dc.identifier.journalBiomaterialsen
ref.citationcount42 [Scopus, 19/05/2010]en
or.citation.harvardHiller, J. et. al. (2003) 'Bone mineral change during experimental heating: an X-ray scattering investigation', Biomaterials, 24 (28), pp.5091-5097.-
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